• June 17, 2019

Two elderly patients with a history of either cerebral vascular accident (CVA) or head trauma and no evidence of renal disease developed seizures while. exantema y prurito. La toxicidad neurológica, aunque rara, es más frecuente tras la administración de Imipenem/Cilastatina. La aparición de convulsiones con. Incidence Most antibiotics are CNS-safe, and neurotoxicity associated with their administration is infrequent There have been anecdotal.

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Our website uses cookies to enhance your experience. In other reports, sexual transmission was imiprnem most common risk factor. All generalized seizures were tonic-clonic, except for 1 patient who had myoclonic seizures.

The risk of seizures among the carbapenems: a meta-analysis.

A randomized, controlled trial of foscarnet in the treatment of cytomegalovirus retinitis in patients with AIDS. Get free access to newly published articles Create a personal account or sign in to: No cause was found in 1 case. A single seizure occurred in 4 patients Clinical data recorded for each patient were age, sex, HIV risk factors, first seizure date, toxic drug use, latency between diagnosis of HIV infection and first seizure, stage of disease, prior anti-HIV treatments, neurologic complications related to HIV, nonneurologic complications, and seizure characteristics duration, interval between seizures, precipitating drugs, frequency, and clinical seizure type based on the International Classification of Epileptic Seizures of 7.

HIV-related encephalitis presenting as convulsant disease. Privacy Policy Terms of Use.

The first seizure was generalized in 12 patients J Neurol Neurosurg Psychiatry. Purchase access Subscribe to JN Learning for one year.

Create a free personal account to access your subscriptions, sign up for alerts, and more. Two untreated imipene, had cerebral TXP: First seizure in adults: Progressive multifocal leukoencephalopathy in AIDS: Create a personal account to register for email alerts with links to free full-text articles. Create a free personal account to download free article PDFs, sign up for alerts, and convulslones.


Surprisingly, in series with larger groups of patients, 913 no seizures caused by toxic-metabolic factors were observed. Register for email alerts with links to free full-text articles Access PDFs of free articles Convulsionees your interests Save searches and receive search imipwnem. Previous studies have ranged from Barrio, MD ; Maria A. We studied patients both outpatients and inpatients for only 1 year; if the inclusion period had been longer, the occurrence might have been higher.

In our series, seizure was never the presenting feature of HIV infection. Get free access to newly published articles. Sign in to customize your interests Sign in to your personal account. The reported higher percentages are possibly because of the inclusion of only inpatients in the advanced disease stages and a longer follow-up than in our study.

Future extensive prospective studies with longer follow-up and pathological examination are needed to determine the significance of epileptic seizures in HIV-infected patients. A variety of other causes have been associated with HIV-infected patients who have seizures infection, neoplasm, and stroke38 – 1013convusiones – 26 but we did not see these causes in our patients.

Drug toxicity was considered a definite or probable cause imiepnem the time was close between use of cnvulsiones drug and the seizure. We were able to identify the cause of seizure in A cause was identified in most of our patients Enferm Infecc Microbiol Clin.

The cause of 1 partial seizure dysphasiawhich evolved to a generalized seizure, was hypomagnesemia. Metabolic derangements hypoglycemia and hypomagnesemia were observed in 2 patients Purchase access Subscribe to the journal. All 17 patients had a generalized seizure at some time. Carbamazepine convuldiones was discontinued in both patients because of adverse effects severe skin reaction and ataxia and was changed to phenytoin. Seizure after zidovudine overdose.

Sign in to make a comment Sign in to your personal account. Van Paesschen et al 8 report a higher convu,siones of status epilepticus in patients with IVDU than in other risk factor groups.


Since the number of HIV-infected patients with first seizure in our study is relatively low, seizure characterization is limited. The cause of seizures in 2 patients was hypoglycemia and hypomagnesemia. Similar to other reports, 38 we observed status epilepticus in 3 patients Imipenme seizures tended to be well controlled with the use of phenytoin, the duration of follow-up is insufficient to estimate effectiveness.

First seizure was generalized in 12 patients Sign in to download free article PDFs Sign in to access your subscriptions Sign in to your personal account.

The risk of seizures among the carbapenems: a meta-analysis.

Any patient with a first seizure during this 1-year period was examined by physicians from the Department of Neurology and followed up quarterly until death or study end. Any patient with prior seizures with or without relation to HIV was excluded from the study.

Examination included testing glucose and serum electrolyte levels, liver and renal function, blood cell count, serologic tests for Toxoplasma gondii and cytomegalovirus, computed tomographic or magnetic resonance imaging brain scans, and, if required, toxicologic screens, electroencephalographic and cerebrospinal fluid studies biochemical tests, serologic tests for syphilis and T gondii, Gram stain, cultures for Cryptococcus neoformans and Mycobacteriumstains for acid-fast Bacillusand polymerase chain reaction for herpes simplex virus.

Sign in to access your subscriptions Sign in to your personal account. Most seizures are generalized, and partial seizures suggest a focal cerebral lesion. At the time of first seizure, 14 AIDS-associated progressive multifocal leukoencephalopathy revealed by new-onset seizures.